Biologicals | Diagnostic Kits | Drug | Medical Devices | The Drug Development Process – From Conception to Market · CliniexpertsThe Drug Development Process –From Conception to Market Drug development encompasses the entire process of bringing a new drug to market. The drug discovery journey starts with the identification of a disease or disease area with an unmet medical need and ends with regulatory submissions and market launch. This article explores the process of drug Phase 1 TrialPhase 2 TrialPhase 3 TrialPhase 4 Trial (PMS)Drug - SND
Biologicals | Drug | Covid-19 vaccines approved for use in India – What you need to know · CliniexpertsCovid-19 vaccines approved for use in India – What you need to know Indian, one of the leaders in the pharmaceutical sector, is set to play a vital role in the global COVID-19 vaccination effort.On 03 January 2021, the Drugs Controller General of India (DCGI) granted emergency approval for two COVID-19 vaccines –Covishield and Covaxin. BiologicalsPhase 1 TrialPhase 2 TrialPhase 3 TrialRegulatory CDSCO
Biologicals | Phase 2-3 Clinical Trials for Covaxin To Commence On Children Aged 2-18 Years Soon · Cliniexperts Phase 2-3 Clinical Trials for Covaxin To Commence On Children Aged 2-18 Years Soon On the 13th of May, 2021, as per one of the country’s top health officials, India’s very first trial of a domestically manufactured Covid-19 vaccine is all set to commence on children in the next 10-12 days. At the forefront Phase 2 TrialPhase 3 TrialVaccines
Biologicals | COVID-19 – Can patent waivers increase vaccine coverage? · CliniexpertsCOVID-19 – Can Patent Waivers Increase Vaccine Coverage? With the new virus variant causing a surge in infections, India has been crippled by the pandemic. Apart from the shortage of medicines, oxygen and healthcare staff, several states in India face a shortage of vaccines – one of the most effective tools to end the pandemic. Biologicals VaccinesGlobal Clinical TrialLocal Clinical TrialVaccines
Biologicals | Consumer Claims | Diagnostic Kits | Drug | Medical Devices | Effective Site Management in Clinical Research – Points to Consider · CliniexpertsEffective Site Management in Clinical Research – Points to Consider Clinical trials are essential to deliver new therapies and advance medical knowledge and patient care. A key aspect of a successful clinical trial is the efficient management of clinical sites. Site management in clinical research Efficient site management is essential to ensure that the clinical Global Clinical TrialLocal Clinical TrialSite ManagementSite Management
Biologicals | Biosimilars in India – Things you need to know · CliniexpertsBiosimilars in India – Things you need to know Biological agents show significant clinical benefits, but their high cost limits their accessibility. The demand for cost-effective options and the patent expiry of biologics have propelled the development of biosimilars or similar biologics. This article covers the key takeaways from the Indian regulatory guidelines for the BiologicalsBlood productsrDNA ProductsRegulatory CDSCOStem cells and cell-based products
Biologicals | Consumer Claims | Diagnostic Kits | Drug | Medical Devices | Conducting clinical trial during COVID-19 · CliniexpertsConducting Clinical Trial during COVID-19 COVID-19 has caused a massive shift in how we manage clinical trials. Due to inadequate resources and restrictions placed due to the pandemic, companies are struggling to maintain the safety of study participants and staff while ensuring the continuity of ongoing trials. The pandemic also paved the way for new Drug - SNDDrug-FDCDrug-INDDrug-New DrugDrug-Phytopharmaceuticals
Biologicals | Diagnostic Kits | Drug | Medical Devices | Online submission of SAE reports through SUGAM portal · CliniexpertsOnline submission of SAE reports through SUGAM portal The New drugs and clinical trials rules, 2019, requires that the investigator, sponsor / CT-NOC holder and ethics committee report all serious adverse events (SAE’s) to the Central Licensing Authority (CLA) within a specified time-frame. CDSCO, through the SUGAM portal, started the process of electronic submissions of BiologicalsDiagnostic KitsDrugMedical DevicesPhase 4 Trial (PMS)
Biologicals | COVID-19 Vaccine Development: Key Developments in India · Cliniexperts COVID-19 Vaccine Development: Key Developments in India The Covid-19 emergency has propelled a race for preventive vaccines and treatment, with numerous efforts by companies, commercial consortia, and scientific organizations worldwide. India is a hub for vaccine production and produces 60 percent of the world’s vaccines. Indian companies have played a pivotal role in producing Global Clinical TrialLocal Clinical TrialRegulatory CDSCOVaccines
Biologicals | Clinical Trials For COVID-19 · Cliniexperts Clinical Trial For Coronavirus COVID-19 The COVID-19 pandemic continues to spread globally despite lockdowns and restrictions. The lack of definitive treatment for the deadly virus has propelled research towards a multipronged approach to mitigate transmission, morbidity, and mortality. In response to the global emergency, clinical trials assessing the efficacy and safety of interventions to Global Clinical TrialLocal Clinical TrialVaccines
Biologicals | Key Insights from the Genome Analysis of the Novel Coronavirus · Cliniexperts Key Insights from the Genome Analysis of the Novel Coronavirus Ever since the first reports of COVID-19 in Wuhan, China, there has been considerable discussion and “debates” on the origin of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the causative virus of COVID-19. In January this year, China shared the full RNA sequence rDNA Products
Biologicals | Vaccines for COVID-19: Time to Fast-Track · CliniexpertsVaccines for COVID-19: Time to Fast-Track While most people are experiencing lockdown blues, scientists worldwide are working endlessly towards developing a viable vaccine for Covid-19 to knock down SARS-CoV-2, the deadly coronavirus. Research at a molecular level would help us understand the virus lifecycle and enhance our preparedness to develop strategies against SARS-CoV-2. Vaccines are Vaccines
Biologicals | Drug | GSR Notification #227: Paving the Way to Clinical Research in India (Part II) · CliniexpertsThe application for permission to conduct clinical research India of a new drug or investigational new drug has to be made in Form CT-04 in place of Form 44. The following are the new provisions to be followed during clinical trials’ conduction in India. Clinical Trials Enrolment Status The clinical trial enrolment status of the CTRIEthics CommitteeFDCNew DrugPhase 4 Trial (PMS)
Biologicals | Drug | GSR Notification #227: Paving the Way to Clinical Research India (Part I) · CliniexpertsThe New Drugs and Clinical Trials Rules, 2019 was declared by the ministry of health and family welfare on 25th March 2019 (GSR Notification #227). The key focus of the new set of rules is to encourage advances in clinical research India. The rules are meant to revolutionize the regulatory aspects for the conduct of CTRIEthics CommitteeFDCNew DrugPhytopharmaceuticals
Biologicals | Human Vaccines – Vaccines Developmental Paradigm India · CliniexpertsVaccines are one of the most beneficial and valuable disease prevention measures contributing to long-term health gains. Advancements in research have led to the development of novel vaccines and delivery technologies and this is has caused a paradigm shift in the way diseases are prevented and treated. Even though the field of vaccines have evolved Blood productsCTRIEthics CommitteePhase 1 TrialPhase 2 Trial
Biologicals | Drug | Medical Devices | Periodic Safety Update Report (PSUR Consideration) · CliniexpertsPeriodic safety update reports (PSUR Consideration) are pharmacovigilance documents that allow a periodic but comprehensive assessment of the risk-benefit balance of a medicinal product after it is marketed. The main purpose of the PSUR is to identify new or emerging safety information, as a means of determining changes in the benefit-risk profile of the authorised Phase 4 Trial (PMS)